| Project/Area Number |
25750208
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Rehabilitation science/Welfare engineering
|
|---|
| Research Institution | Sapporo Medical University |
|---|
Principal Investigator |
IWAMOTO Erika 札幌医科大学, 保健医療学部, 助教 (40632782)
|
|---|
| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
|
|---|
| Keywords | 血管内皮機能 / 電気刺激 / 温熱 / 血流 / 血流依存性血管拡張反応 / 動脈 / 温熱刺激 / 併用刺激 / 順行性血流 / 逆流性血流 / 血管機能 / 非活動部位 |
|---|
| Outline of Final Research Achievements |
Accumulating evidence suggests that endothelial dysfunction is an early marker for atherosclerosis. Improvement in endothelial function is associated with a decrease in atherosclerotic vascular diseases. The aim of this study was to assess the effects of dry heating, electrical stimulation and the combination of dry heating and electrical stimulation on the endothelial function in the brachial artery. We measured flow-mediated dilation (FMD) as an index of vascular function before and after 30 min of each trial. A combination of dry heating and electrical stimulation significantly increased FMD in the brachial artery. However, no significant changes were observed after only dry heating or electrical stimulation. This study revealed that the combination of dry heating and electrical stimulation is effective in improving conduit vasodilator function.
|
