| Project/Area Number |
25750232
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Nagoya Gakuin University |
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Principal Investigator |
SHIRO Yukiko 名古屋学院大学, リハビリテーション学部, 講師 (30440663)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 運動 / 鎮痛 / 自律神経 / 脳波 / 慢性痛 / 自律神経活動 / 運動イメージ / 運動錯覚 / 疼痛抑制 |
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| Outline of Final Research Achievements |
Changes in mechanical sensitivity can occur in response to exercise in healthy subjects and may involve multiple interacting peripheral and central pain-modulatory mechanisms. In contrast, the experimental pain rating of patients with chronic pain increased after exercise, thereby suggesting abnormal pain modulation. We aimed to investigate the effect of exercise-induced hypoalgesia (EIH) using electroencephalography and sympathetic nerve activity in patients with chronic pain compared with that in healthy controls. The effect of EIH depended on the level of attention demand and sympathetic nerve activity during exercise. However, EIH and sympathetic nerve activity to the exercise decreased in patients with chronic pain. Therefore, abnormal sympathetic nerve activity could be factor of chronic pain.
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