Effects of fiber-rich diet with brown rice on endothelial function
Project/Area Number |
25750346
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Applied health science
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Research Institution | Shiga University of Medical Science |
Principal Investigator |
KONDO KEIKO 滋賀医科大学, 医学部, 特任助教 (20566567)
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Project Period (FY) |
2013-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2016: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Keywords | 食事介入 / 玄米 / 血管内皮機能 / 2型糖尿病 / 食物繊維 / 糖尿病 |
Outline of Final Research Achievements |
Twenty-eight patients with type 2 diabetes mellitus were randomly assigned to a brown rice (n=14) or white rice (n=14) diet and were followed for 2 months. After intervention, both groups were followed by white rice diet for 2 months. In the brown rice group, the intake of dietary fiber increased after the intervention and decreased after the follow-up period. The levels of fasting plasma glucose, glycoalbumin, and, total and LDL-cholesterol improved after the intervention and returned to the baseline levels after the follow-up period in brown rice group. Endothelial function significantly improved after the intervention and these effects were sustained after the follow-up period in the brown rice group, although metabolic parameters were returned to the baseline levels after the follow-up period. This study suggested the intervention with brown rice improves endothelial function. The effect was sustained for an additional 2 months after stopping the intervention in type 2 diabetes.
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Report
(5 results)
Research Products
(8 results)
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[Presentation] Post-prandial Improvement in Endothelial Function by Brown Rice Diet Intervention in Patients with Type 2 Diabetes Mellitus.2015
Author(s)
Keiko Kondo, Katsutaro Morino, Atsushi Ishikado, Keiko Nakao, Fumiyuki Nakagawa, Fumio Nikami, Osamu Sekine, Ken-ichi Nemoto, Makoto Suwa, Motonobu Matsumoto, Taketoshi Makino, Atsunori Kashiwagi, Satoshi Ugi, Hiroshi Maegawa
Organizer
The 75th American Diabetes Association
Place of Presentation
Boston, MA, America
Year and Date
2015-06-05
Related Report
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[Presentation] Improvement of Endothelial Function by Brown Rice Diet was Associated with Change of Gut Microflora Composition in Patients with Type 2 Diabetes Mellitus.2014
Author(s)
Keiko Kondo, Katsutaro Morino, Atsushi Ishikado, Keiko Nakao, Fumio Nikami, Osamu Sekine, Ken-ichi Nemoto, Motonobu Matsumoto, Taketoshi Makino, Atsunori Kashiwagi, Satoshi Ugi, Hiroshi Maegawa
Organizer
The 74th American Diabetes Association
Place of Presentation
San Francisco, CA, America
Year and Date
2014-06-13 – 2014-06-17
Related Report
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[Presentation] 玄米を用いた高繊維食は糖尿病患者の血管内皮機能を改善する2014
Author(s)
近藤慶子, 森野勝太郎, 石角 篤, 中尾恵子, 仁神史生, 関根 理, 根本憲一, 松本元伸, 牧野武利, 柏木厚典, 卯木 智, 前川 聡
Organizer
第57回 日本糖尿病学会年次学術総会
Place of Presentation
大阪
Year and Date
2014-05-22 – 2014-05-24
Related Report
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