Effects of flexibility levels and age on stretching exercise- induced changes in arterial stiffness

• Project/Area Number: 25750363
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Applied health science
• Research Institution: National Institutes of Biomedical Innovation, Health and Nutrition (2015); National Institute of Health and Nutrition (2014); Waseda University (2013)
• Principal Investigator: Gando Yuko 国立研究開発法人医薬基盤・健康・栄養研究所, 国立健康・栄養研究所 健康増進研究部, 研究員 (60613932)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
• Keywords: 動脈壁硬化 / ストレッチング / 柔軟性 / 加齢 / 動脈スティフネス

Outline of Final Research Achievements

(1)The purpose of this study was to determine the effects of flexibility levels on changes in arterial stiffness induced by stretching exercise.(2)The purpose of this study was to determine the acute effects of stretching exercise on arterial stiffness, blood pressure, and heart rate in younger and older adults.The results suggested that (1) stretching exercise acutely decreases arterial stiffness regardless of flexibility levels. (2) stretching exercise acutely increases blood pressure and arterial stiffness and decreases heart rate in both age groups.

Research Products

• [Journal Article] Cardiorespiratory Fitness Suppresses Age-Related Arterial Stiffening in Healthy Adults: A 2-Year Longitudinal Observational Study (2016)
  • Author(s): Gando Y, Murakami H, Kawakami R, Yamamoto K, Kawano H, Tanaka N, Sawada SS, Miyatake N, Miyachi M
  • Journal Title: Journal of Clinical Hypertension Volume: 18 Issue: 4 Pages: 292-298
  • DOI: 10.1111/jch.12753
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Higher cardiorespiratory fitness attenuates the risk of atherosclerosis associated with adrb3 trp64arg polymorphism (2014)
  • Author(s): Iemitsu M, Fujie S, Murakami H, Sanada K, Kawano H, Gando Y, Kawakami R, Tanaka N, Miyachi M
  • Journal Title: Eur J Appl Physiol Volume: 114 Pages: 1421-1428
  • Peer Reviewed
• [Journal Article] The q223r polymorphism in the leptin receptor associates with objectively measured light physical activity in free-living japanese (2014)
  • Author(s): Murakami H, Iemitsu M, Fuku N, Sanada K, Gando Y, Kawakami R, Miyachi M
  • Journal Title: Physiology & behavior Volume: 129 Pages: 199-204
  • Peer Reviewed
• [Journal Article] Light-intensity physical activity is associated with insulin resistance in elderly Japanese women independent of moderate- to vigorous-intensity physical activity (2014)
  • Author(s): Gando Y, Murakami H, Kawakami R, Tanaka N, Sanada K, Tabata I, Higuchi M, Miyachi M.
  • Journal Title: J Phys Act Health Volume: 11 Pages: 266-271
  • Peer Reviewed
• [Journal Article] Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women (2014)
  • Author(s): Koitaya N, Sekiguchi M, Tousen Y, Nishide Y, Morita A, Yamauchi J, Gando Y, Miyachi M, Aoki M, Komatsu M, Watanabe F, Morishita K, Ishimi Y
  • Journal Title: J Bone Miner Metab Volume: 32 Pages: 142-150
  • Peer Reviewed
• [Journal Article] Home-Based Active Video Games to Promote Weight Loss during the Postpartum Period (2014)
  • Author(s): Tripette J, Murakami H, Gando Y, Kawakami R, Sasaki A, Hanawa S, Hirosako A, Miyachi M.
  • Journal Title: Med Sci Sports Exerc Volume: 46 Pages: 472-478
  • Peer Reviewed
• [Journal Article] Lack of age-related increase in carotid artery wall viscosity in cardiorespiratory fit men (2013)
  • Author(s): Kawano H, Yamamoto K, Gando Y, Tanimoto M, Murakami H, Ohmori Y, Sanada K, Tabata I, Higuchi M, Miyachi M.
  • Journal Title: J Hypertens Volume: 31 Pages: 2370-2379
  • Peer Reviewed
• [Presentation] Trunk flexibility and the incidence of hypertension: A cohort study in japanese men and women (2015)
  • Author(s): Gando Y, Sawada S, Matsushita M, Kawakami R, Miyachi M, Tashiro M, Lee I, Blair S
  • Organizer: American College of Sport Medicine 62th Annual Meeting
  • Place of Presentation: San Diego-USA
  • Year and Date: 2015-05-27
  • Int'l Joint Research
• [Presentation] Cardiorespiratory fitness and incidence of hypertension: A long term cohort study of japanese men (2015)
  • Author(s): Gando Y, Sawada S, Kawakami R, Matsushita M, Okamoto T, Tsukamoto K, Miyachi M
  • Organizer: 第25回日本疫学会学術総会
  • Place of Presentation: 愛知県
  • Year and Date: 2015-01-21 – 2015-01-23
• [Presentation] Influence of sex on stretching exercise-induced reduction in arterial stiffness (2013)
  • Author(s): Gando Y, Yamamoto K, Kawano H, Hara R, Muraoka I
  • Organizer: 18th annual Congress of the European College of Sport Science
  • Place of Presentation: Spain-Barcelona