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Nutritional effects of the blood glucose change and the abnormal behavior in rats

Research Project

Project/Area Number 25750370
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Applied health science
Research InstitutionKio University (2014)
University of Shizuoka (2013)

Principal Investigator

MURAKI Etsuko  畿央大学, 健康科学部, 准教授 (80369157)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords耐糖能異常 / 異常行動 / 精神神経疾患 / 耐糖能 / 血糖変動 / グルコース負荷試験 / インスリン負荷試験 / オープンフィールド / 低血糖 / 抑うつ
Outline of Final Research Achievements

It is reported that the hypoglycemia is similar to depression. And it is reported in the patients with diabetes and impaired glucose tolerance to be easy to have depression. Furthermore, it is easy to have diabetes and impaired glucose tolerance in the patients with depression. In this study, I elucidate glucose tolerance and abnormality of the carbohydrate metabolism and relations of the psycho-neurologic disease. Therefore I examined the blood glucose change and effect on mood symptoms in patients with depression. And I examined effect on behavior change and internal secretion in the rat with a sudden blood glucose change. As a result, glucose tolerance and the central nerve symptom at impaired hypoglycemia were found in the patients with depression. However, the rat that blood glucose made it fluctuate had few effect on abnormal behavior and internal secretion.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (1 results)

All 2014

All Presentation (1 results)

  • [Presentation] 気分障害患者を対象とした5時間耐糖能試験における血糖変動の予備的検討2014

    • Author(s)
      2. 村木悦子, 横田悠季, 服部功太郎, 瀬川和彦, 功刀浩, 吉田寿美子
    • Organizer
      第17回日本病態栄養学会年次学術集会
    • Place of Presentation
      大阪国際会議場
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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