Daily physical activity or exercise habit and the gene polymorphisms on dopamine system.
| Project/Area Number |
25750371
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | National Institute of Health and Nutrition |
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Principal Investigator |
MURAKAMI Haruka 独立行政法人国立健康・栄養研究所, 健康増進研究部, 研究員 (20344880)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 身体活動 / 運動 / 遺伝 / ドーパミン / 行動 / 運動習慣 / ドーパミンシステム / 遺伝子多型 |
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| Outline of Final Research Achievements |
The porpose of this study was to investigate the relation between daily physical activity or exercise habit and the gene polymorphisms on dopamine system. Eighty-hundred one healthy adults and 604 athletes participated in this study. DRD2/ANKK1 gene polymorphism rs1800497 was associated with exercise habit in the period from childhood to adolescence. This polymorphism was also associated with athlete level only in male athletes, but not in female athletes. The T allele was associated with an increased likelihood of the international/national level in the additive genetic model (OR = 1.67, 95%CI: 1.15-2.41). Moreover the other two polymorphisms on DRD2 gene was associated with daily physical activity assessed using tri-accelerometer. it was suggested that the dopamine system is involved in determination of daily physical activity or exercise habit.
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Report
(3 results)
Research Products
(8 results)
