| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
The porpose of this study was to investigate the relation between daily physical activity or exercise habit and the gene polymorphisms on dopamine system. Eighty-hundred one healthy adults and 604 athletes participated in this study. DRD2/ANKK1 gene polymorphism rs1800497 was associated with exercise habit in the period from childhood to adolescence. This polymorphism was also associated with athlete level only in male athletes, but not in female athletes. The T allele was associated with an increased likelihood of the international/national level in the additive genetic model (OR = 1.67, 95%CI: 1.15-2.41). Moreover the other two polymorphisms on DRD2 gene was associated with daily physical activity assessed using tri-accelerometer. it was suggested that the dopamine system is involved in determination of daily physical activity or exercise habit.
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