| Project/Area Number |
25750405
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Basic / Social brain science
|
|---|
| Research Institution | University of Fukui |
|---|
Principal Investigator |
FUJISAWA Takashi 福井大学, 子どものこころの発達研究センター, 特命助教 (90434894)
|
|---|
| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
|---|
| Keywords | 思春期 / 青年期 / 衝動性 / 実行機能 / 認知的制御 / 社会的ストレス / 脳イメージング / 性腺ホルモン |
|---|
| Outline of Final Research Achievements |
This study investigated the neural mechanism underlying development of tolerance for social stress or enhancement of impulsive behavior during adolescence and the deviant behavior. As a result, 1) we developed a model of the tolerance for social stress by conducting large-scale survey, and examined the validity. 2) In a brain imaging study for adolescents with adverse experiences, they have decreased striatal activity during reward processing. The results suggested that dopaminergic dysfunction occurred in the striatum in children and adolescents with adversity, potentially leading to a future risk of psychiatric disorders, such as dependence. 3) In a brain imaging study for adults, we found that individuals with higher tolerance for social stress demonstrated stronger connectivity within executive functional network.
|
