Design and control of dynamic propeller chirality based on terephthalamides
| Project/Area Number |
25810017
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Organic chemistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
KATOONO Ryo 北海道大学, 理学(系)研究科(研究院), 助教 (60432142)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 分子プロペラ / 動的キラリティ / 動的らせん性 / テレフタルアミド / ホスト-ゲスト / 立体特異的構造変化 / らせん性反転 / 面不斉 |
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| Outline of Final Research Achievements |
We have designed and synthesized dynamic molecules with propeller chirality based on a terephthalamide skeleton. The two amide groups in a terephthalamide unit acted as a binding site for caputuring a ditopic guest through the formation of hydrogen bonds, and contributed to creation of chiroptical signals when the guest was chiral, or a chiral auxiliary was attached to the terephthalamide unit(s).
We have demonstrated chiroptical signals based on dynamic molecular propellers.
In a complexed state, a particular sense of dynamic propeller chirality was predominantly favored over the other, and exhibited chiroptical signals.
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Report
(3 results)
Research Products
(18 results)
