| Project/Area Number |
25810051
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Functional solid state chemistry
|
|---|
| Research Institution | Kyushu University |
|---|
Principal Investigator |
NOGUCHI Takao 九州大学, 工学(系)研究科(研究院), 学術研究員 (00632431)
|
|---|
| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Keywords | 蛍光センサ / 会合誘起発光 / 自己集合 / 分子情報変換 / ATP / ジカルボン酸 / 代謝疾患 / スクリーニング / NADPH |
|---|
| Outline of Final Research Achievements |
A new perspective of self-assembly was offered, in which self-assembly works as a functional system to translate the structural information on the target, via self-assembly morphology, eventually into the FL optical output. This cascade realized the fluorometric readout of a subtle difference in the target structures such as nucleotides and dicarboxylates. This study unveiled the potential ability of self-assembly as a sensory system, thus demonstrating a new fluorescence sensing system utilizing self-assembly phenomena.
|
