Probing the mechanism and application of NMR chiral sensing based on achiral molecules
| Project/Area Number |
25810055
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Functional solid state chemistry
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| Research Institution | National Institute for Materials Science |
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Principal Investigator |
ISHIHARA Shinsuke 独立行政法人物質・材料研究機構, 国際ナノアーキテクトニクス研究拠点, NIMSポスドク研究員 (30644067)
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| Co-Investigator(Renkei-kenkyūsha) |
LABUTA Jan 独立行政法人物質・材料研究機構, 若手国際センター, ICYS研究員 (00720690)
HILL Jonathan 独立行政法人物質・材料研究機構, 国際ナノアーキテクトニクス研究拠点, MANA Scientist (30421431)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | キラル / 不斉認識 / NMR / 分子認識 / センサー / ポルフィリン / 核磁気共鳴分光法 |
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| Outline of Final Research Achievements |
We have developed a oxoporphyrinogen derivative, which can be available as NMR chiral solvating agent of various chiral molecules. NMR split of oxoporphyrinogen has linear relationship between enantiomeric excess % of chiral molecules. Based on theoretical calculations, we proved that chiral sensing is based on magnetic anisotropy induced by chiral molecule, and also average of the anisotropy upon fast exchange equilibrium.
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Report
(3 results)
Research Products
(4 results)
