| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
Cell membrane potential plays a crucial role in cellular functionｓ in various cells such as nerve cells. Therefore, artificial control on the membrane potential is promising technology for cellular engineering and medical applications. For the control, we have studied on organic molecules which can generate charge separated state by irradiation in cellular environment. As a fruit, we found a molecular system which display efficient charge separation (quantum yield = 41%). In a series of study revealed that the molecules can induce depolarization in membrane of PC12 and rat hippocampal neurons. In addition, the degrees parallel the charge separation efficiency.
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