The role of alpha2-antiplasmin in memory formation and dendritic growth
Project/Area Number |
25830057
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Neurochemistry/Neuropharmacology
|
Research Institution | Doshisha Women's College of Liberal Arts |
Principal Investigator |
KAWASHITA Eri 同志社女子大学, 薬学部, 助教 (80509266)
|
Project Period (FY) |
2013-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | α2-antiplasmin / 記憶 / 樹状突起 / 神経細胞 / α2アンチプラスミン / 線維素溶解系因子 |
Outline of Final Research Achievements |
We found that α2-Antiplasmin (α2AP) is a crucial mediator of cognitive function. We also demonstrated that α2AP induces dendritic growth in hippocampal neurons through p38 MAPK activation, independent of plasmin.
|
Report
(3 results)
Research Products
(7 results)