Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Outline of Final Research Achievements |
While the contribution of blood platelets to carcinogenesis has been known for more than a century, the molecular mechanisms through which they do so remain poorly understood. Our work has established that blood platelets have the abilities to fuse with specific cancer cell lines. By fusing with platelets, cancer cells were found to undergo transcriptional reprogramming and display enhanced adhesive abilities. These findings may provide novel therapeutic opportunities for the treatment of metastatic cancer.
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