| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Using Iberian ribbed newt that is useful a model animal for regeneration biology, we established a cell lineage tracing system by genetic labeling. We showed the pre-existing cardiomyocytes proliferated during cardiac regeneration in the newts. We reported that TALEN-mediated gene targeting and an infrared laser mediated local gene induction by IR-LEGO system in the P. waltl. Moreover, we prepared basic data for genome editing in the newts in order to establish conditional knock-out system that enable more detailed analysis in organ regeneration.
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