| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Outline of Final Research Achievements |
To identify the brain loci essential for the spatial learning and memory in an amphibious teleost mudskipper by using immunostaining for cFos protein which is induced the expression following to neuronal activity, we designed a “Morris water maze-like task” for mudskipper, based on their amphibious property by improving a general task for rodents. The number of cFos-expressing neuron in the telencephalic dorsolateral (Dl) and dorsocentral (DC) region of the brain was increased in the mudskippers acquiring spatial learning and memory through the task, suggesting that these regions may play an important role for the spatial learning and memory in mudskipper. However, an increase of newborn neurons in the concerned regions was not observed even after acquiring the spatial learning and memory. We are now trying to improve the task to obtain clear findings.
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