| Project/Area Number |
25840121
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | Okayama University |
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Principal Investigator |
YOSHII Taishi 岡山大学, 自然科学研究科, 准教授 (50611357)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 概日時計 / 体内時計 / キイロショウジョウバエ / 時間生物学 / 時計細胞 / 神経ペプチド / RNA干渉 / RNA干渉法 |
|---|
| Outline of Final Research Achievements |
In Drosophila melanogaster, the molecular mechanism of circadian clock has been well investigated. However, its neuronal mechanism still remains elusive. The Drosophila brain contains about 150 neurons that are responsible for circadian rhythms in behavior. The motivation of this study is to understand how the circadian clock neurons read out time information, which they generate, to downstream neurons. Here, we found that ITP and CCHa1 are new candidate peptides that function as output factors of the clock neurons.
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