Elucidation of epigenetic mechanism that regulates a neural circuit for C. elegans behavioral plasticity
| Project/Area Number |
25840124
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Genetics/Chromosome dynamics
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| Research Institution | Kyoto University |
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Principal Investigator |
SUGI Takuma 京都大学, 物質-細胞統合システム拠点, 助教(特任) (70571305)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | 記憶 / エピジェネティクス / 線虫C. elegans / 線虫 |
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| Outline of Final Research Achievements |
In this study, I investigated a mechanistic relationship between epigenetics and behavioral memory in C. elegans. I initially developed a multiplexed optical system to genetically analyzed C. elegans mechanosensory habituation in a high-throughput manner. Then, using this system, I identified two interneurons involved in memory formation, and an epigenetic factor important for memory formation.
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Report
(3 results)
Research Products
(11 results)
