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Development of enantioselective oxidation of glycerol by microbial fermentation for efficient utilization of raw glycerol and its application to functional chemicals

Research Project

Project/Area Number 25850064
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Applied microbiology
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

SATO Shun  独立行政法人産業技術総合研究所, 環境化学技術研究部門, 主任研究員 (10586605)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywordsグリセリン酸 / グリセリン / メタノール / 酢酸菌 / アシルグリセリン酸
Outline of Final Research Achievements

Glycerol becomes alternative and attractive feedstock for chemical production due to rapid increase of biodiesel fuel utilization. Some acetic acid bacteria are known to produce large amount of D-glyceric acid from glycerol. However, raw glycerol derived from biodiesel fuel production contains impurities like methanol, which would cause a sever decrease in yield of glyceric acid. In this study, enentioselective oxidation of glycerol derived from biodiesel fuel production was investigated by using a methanol-assimilating acetic acid bacterium. Application of glyceric acid to functional chemicals was also investigated.
The methylotrophic acetic acid bacterium used in this study could produce larger amount of glyceric acid from glycerol in the presence of methanol than that in the absence of methanol. Also, glyceric acid was successfully converted to amphihilic compounds, and these compounds showed superior amphipathic properties compared with those of commercial detergents.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2014 2013

All Presentation (3 results)

  • [Presentation] グリセロールを原料とするAcidomonas methanolicaによるグリセリン酸生産2014

    • Author(s)
      佐藤 俊、羽部 浩
    • Organizer
      平成26年度油化学関連シンポジウム
    • Place of Presentation
      琉球大学(沖縄県)
    • Year and Date
      2014-10-31 – 2014-11-01
    • Related Report
      2014 Annual Research Report
  • [Presentation] メタノール資化性酢酸菌によるメタノール含有グリセリンからのグリセリン酸生産2014

    • Author(s)
      佐藤 俊、羽部 浩
    • Organizer
      第3回JACI/GSCシンポジウム
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2014-05-22 – 2014-05-23
    • Related Report
      2014 Annual Research Report
  • [Presentation] メチロトローフ酢酸菌Acidomonas methanolicaのメタノール含有グリセリンからのグリセリン酸生産能2013

    • Author(s)
      佐藤俊、北本大、羽部浩
    • Organizer
      日本油化学会第52会年会
    • Place of Presentation
      東北大学川内北キャンパス
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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