Genome-wide analysis of a relationship between transcription start sites and translational control under heat stress conditions.
| Project/Area Number |
25850069
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied biochemistry
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 翻訳制御 / 転写開始点 / CAGE / シロイヌナズナ / シロイヌナズナ培養細胞 / 環境ストレス / 植物 / CAP構造 / ポリソーム / CAGE解析 |
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| Outline of Final Research Achievements |
In eukaryotes, transcription initiation landscape shows diversity among genes; one gene show dispersed (heterogeneous) transcription start sites (TSS) and the others show focused (homogeneous) TSS. We investigated genome-wide relationship between transcription initiation landscape and translational control in response to abiotic stresses in Arabidopsis thaliana, and found a potential important relationship between the differential transcription initiation landscape and robustness and flexibility of mRNA translational control for stress response.
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Report
(4 results)
Research Products
(9 results)
