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Elucidation of the network of stress responses and skeletal muscle metabolisms by fish energy metabolisms.

Research Project

Project/Area Number 25850142
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Aquatic life science
Research InstitutionTokyo University of Marine Science and Technology

Principal Investigator

Nagasaka Reiko  東京海洋大学, 学術研究院, 助教 (90444132)

Project Period (FY) 2013-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsストレス応答 / 筋代謝 / エネルギー代謝 / 魚類
Outline of Final Research Achievements

The aim of this study is to reveal the effect of energy metabolism to stress response and its relationship to skeletal muscle metabolism. We revealed that stress responses affected muscle metabolism and degradation of extracellular matrix in teleost. In addition, differences in energy metabolisms influenced the muscle metabolisms. Furthermore, there is a possibility that oryzanol activate energy metabolisms in the muscle of zebrafish. As a result of this study, it was suggested that alteration of energy metabolism promotes protein synthesis system, influences autophagy, and has stress relief effect, thereby affecting quality of fish meat.

Report

(6 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (40 results)

All 2018 2017 2016 2015 2014 2013

All Journal Article (8 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 8 results,  Open Access: 2 results) Presentation (29 results) (of which Int'l Joint Research: 3 results) Book (2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Efffect of proteolysis on meat quality of brand fish, red sea bream Pagrus major2018

    • Author(s)
      R. Nagasaka, A. Harigaya, T. Ohshima
    • Journal Title

      Food Science and Technology Research

      Volume: 24 Pages: 465-473

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of ergothioneine-rich mushroom extracts on lipid oxidation and discoloration in salmon muscle stored at low temperatures2017

    • Author(s)
      J. Pahila, H. Kaneda, R. Nagasaka, T. Koyama, T. Ohshima
    • Journal Title

      Food Chemistry

      Volume: 233 Pages: 273-281

    • DOI

      10.1016/j.foodchem.2017.04.130

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 1.Cardio-metabolic Disease Risks and Their Associations with Circulating 25-Hydroxyvitamin D and Omega-3 levels in South Asian and White Canadians2016

    • Author(s)
      Chao-Wu Xiao, Carla M. Wood, Eleonora Swist, Reiko Nagasaka, Kurtis Sarafin, Claude Gagnon, Lois Fernandez, Sylvie Faucher, Hong-Xing Wu, Laura Kenney, Walisundera M.N. Ratnayake
    • Journal Title

      PLoS ONE

      Volume: 11 Issue: 1 Pages: e0147648-e0147648

    • DOI

      10.1371/journal.pone.0147648

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Diversity of lipid distribution in fish skeletal muscle2016

    • Author(s)
      2.Gen Kaneko, Hirohito Shirakami, Yuki Hirano, Moemi Oba, Hazuki Yoshinaga, Anurak Khieokhajonkhet, Reiko Nagasaka, Hidehiro Kondo, Ikuo Hirono, Hideki Ushio
    • Journal Title

      Zoological Science

      Volume: 33 Issue: 2 Pages: 170-178

    • DOI

      10.2108/zs150096

    • NAID

      40020790456

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Depigmenting Effect of Winter Medicinal Mushroom, Flammulna velutipes (Higher Basidiomycetes) on Melanoma Cells2015

    • Author(s)
      Reiko Nagasaka, Yuki Ishikawa, Takumi Inada, & Toshiaki Ohshima
    • Journal Title

      International Journal of Medicinal Mushrooms

      Volume: 17

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] EPA and DHA status of South Asian and White Canadians living in the National Capital Region of Canada2014

    • Author(s)
      Reiko Nagasaka, Claude Gagnon, Eleonora Swist, Isabelle Rondeau, Isabelle Massarelli, Winnie Cheung, Walisundera M.N. Ratnayake
    • Journal Title

      Lipids

      Volume: 49 Issue: 10 Pages: 1057-1069

    • DOI

      10.1007/s11745-014-3942-3

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Utilization of Biological Responses of Fish and Shellfish for Improving Seafood Qualities2013

    • Author(s)
      Hideki Ushio, Reiko Nagasaka
    • Journal Title

      Aqua-BioScience Monographs

      Volume: 6 Issue: 3 Pages: 91-98

    • DOI

      10.5047/absm.2013.00603.0091

    • NAID

      40020197655

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Differences in lipid distribution and expression of peroxisome proliferator-activated receptor gamma and lipoprotein lipase genes in torafugu and red seabream2013

    • Author(s)
      Kaneko G, Yamada T, Han Y, Hirano Y, Khieokhajonkhet A, Shirakami H, Nagasaka R, Kondo H, Hirono I, Ushio H, Watabe S
    • Journal Title

      Gen Comp Endocrinol

      Volume: 184 Pages: 51-60

    • DOI

      10.1016/j.ygcen.2013.01.003

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] ゼブラフィッシュmaxillary barbelにおける味覚受容体発現の解析2018

    • Author(s)
      林風咲子・小林令奈・笠原万有璃・石川雄樹・長阪玲子
    • Organizer
      平成30年度日本水産学会春季大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 食用海藻中に含まれる非タンパク質構成アミノ酸teneraic acidのLC-MS/MS分2018

    • Author(s)
      堀由歩・石川雄樹・大島敏明・長阪玲子
    • Organizer
      平成30年度日本水産学会春季大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 小胞体ストレスによる魚類の筋分化促進に関する研究2017

    • Author(s)
      笠原万有璃・石川雄樹・星剛流・長阪玲子
    • Organizer
      平成28年度日本水産学会大会春季大会
    • Place of Presentation
      東京海洋大学
    • Year and Date
      2017-03-26
    • Related Report
      2016 Research-status Report
  • [Presentation] Associations between red blood cell fatty acids and cardiometabolic risk markers differ in White vs. South Asian Canadian adults living in Ottawa2017

    • Author(s)
      Isabelle Demonty, Cunye Qiao, Chao-Wu Xiao, Eleonora Swist, Reiko Nagasaka, Carla Wood, Walisundera Ratnayake
    • Organizer
      AOCS Annual Meeting
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 魚類の植物フラボノイド蓄積による魚肉機能性負荷についての研究2017

    • Author(s)
      小林令奈・石川雄樹・長阪玲子
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ニジマス初代培養細胞の筋分化に及ぼす小胞体ストレス経路の影響2017

    • Author(s)
      笠原万有璃・石川雄樹・星岡流・細田萌菜美・長阪玲子
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ノリに含まれる非タンパク質構成アミノ酸 teneraic acid の体内動態2017

    • Author(s)
      堀由歩・石川雄樹・横山雄彦・長阪玲子
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ストレス条件下における糖質嗜好性の変動2017

    • Author(s)
      末武綾子・長阪玲子・石川雄樹
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 近赤外蛍光イメージング法を用いた金魚の摂食嗜好性評価2017

    • Author(s)
      林風咲子・石川雄樹・長阪玲子
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ニジマスにおけるストレス応答と魚肉の品質に関する研究2016

    • Author(s)
      長阪玲子・金城春菜・石川雄樹・大島敏明
    • Organizer
      平成28年度日本水産学会大会春季大会
    • Place of Presentation
      東京海洋大学品川キャンパス
    • Year and Date
      2016-03-26
    • Related Report
      2015 Research-status Report
  • [Presentation] シロサケ初期成長に及ぼすオリザノールの効果について2016

    • Author(s)
      長阪玲子・石川雄樹・小山智之・大島敏明
    • Organizer
      平成28年度日本水産学会大会春季大会
    • Place of Presentation
      東京海洋大学品川キャンパス
    • Year and Date
      2016-03-26
    • Related Report
      2015 Research-status Report
  • [Presentation] Estrogenic Efficts of Squid Ink of Shiroika, Sepioteuthis Iessoniana in Okinawa, Japan2015

    • Author(s)
      Haruna Kinjo, Yuki Ishikawa, Reiko Nagasaka
    • Organizer
      International symposium Aquatic Products Proceeding Cleaner Production Chain for Healthier Food
    • Place of Presentation
      Can Tho University
    • Year and Date
      2015-12-07
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Hazuki Nakachi, Yuki Ishikawa, Reiko Nagasaka2015

    • Author(s)
      The Influence of Environmental Temperature on Appetite and Food Intake
    • Organizer
      International symposium Aquatic Products Proceeding Cleaner Production Chain for Healthier Food
    • Place of Presentation
      Can Tho University
    • Year and Date
      2015-12-07
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 米糠中ヒドロキシ桂皮酸類による高尿酸血症予防効果についての検討2015

    • Author(s)
      長阪 玲子,金城 春菜,本田 詩織,石川 雄樹
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Related Report
      2015 Research-status Report
  • [Presentation] 赤外蛍光イメージング法を利用した魚類の植物性飼料摂食性評価についての研究2015

    • Author(s)
      石川 雄樹,大島 敏明,長阪 玲子
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Related Report
      2015 Research-status Report
  • [Presentation] 環境温度が食欲および嗜好性におよぼす影響について2015

    • Author(s)
      中地 はづき,小野寺 柚香,石川 雄樹,長阪 玲子
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Related Report
      2015 Research-status Report
  • [Presentation] 沖縄県産シロイカのイカスミが女性ホルモン動態に及ぼす影響について2015

    • Author(s)
      金城 春菜,中地 はづき,石川 雄樹,長阪 玲子
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Related Report
      2015 Research-status Report
  • [Presentation] 魚類の筋タンパク質分解に関する研究2014

    • Author(s)
      長阪玲子・針ヶ谷敦子・近藤秀裕・廣野育生・金子 元・潮 秀樹
    • Organizer
      平成26年度日本水産学会大会秋季大会
    • Place of Presentation
      九州大学箱崎キャンパス
    • Year and Date
      2014-09-20 – 2014-09-22
    • Related Report
      2014 Research-status Report
  • [Presentation] 金城春菜・石川雄樹・長阪玲子・近藤秀裕・廣野育生・金子 元・潮 秀樹2014

    • Author(s)
      魚類の短期ストレスが及ぼす筋代謝への影響
    • Organizer
      平成26年度日本水産学会大会秋季大会
    • Place of Presentation
      九州大学箱崎キャンパス
    • Year and Date
      2014-09-20 – 2014-09-22
    • Related Report
      2014 Research-status Report
  • [Presentation] 魚肉筋タンパク質の分解に関する研究2014

    • Author(s)
      長阪玲子,針ヶ谷敦子,近藤秀裕,廣野育生,金子元,潮秀樹
    • Organizer
      平成26年度日本水産学会春季大会
    • Place of Presentation
      北海道大学(函館キャンパス)
    • Related Report
      2013 Research-status Report
  • [Presentation] 魚類における生育温度が及ぼす脂質代謝への影響2014

    • Author(s)
      中地はづき,石川雄樹,長阪玲子,大島敏明
    • Organizer
      平成26年度日本水産学会春季大会
    • Place of Presentation
      北海道大学(函館キャンパス)
    • Related Report
      2013 Research-status Report
  • [Presentation] γオリザノールの経口投与がニジマスのエネルギー代謝に及ぼす影響2014

    • Author(s)
      Han Yuna,金子元,潮秀樹,長阪玲子,近藤秀裕,廣野育生
    • Organizer
      平成26年度日本水産学会春季大会
    • Place of Presentation
      北海道大学(函館キャンパス)
    • Related Report
      2013 Research-status Report
  • [Presentation] 魚類のストレス応答が及ぼす筋代謝への影響2014

    • Author(s)
      金城春菜,石川雄樹,長阪玲子,近藤秀裕,廣野育生,金子元,潮秀樹
    • Organizer
      平成26年度日本水産学会春季大会
    • Place of Presentation
      北海道大学(函館キャンパス)
    • Related Report
      2013 Research-status Report
  • [Presentation] キノコ抽出液添加飼料が卵の品質改善に及ぼす影響2014

    • Author(s)
      孫 禎晧,長阪玲子,小山智之,滝沢栄喜・阿部一成・大島敏明
    • Organizer
      家禽学会2014年度春季大会
    • Place of Presentation
      筑波大学
    • Related Report
      2013 Research-status Report
  • [Presentation] Roles of apoptosis and autophagy on the texture of red seabream muscle2013

    • Author(s)
      Atsuko Harigaya, Reiko Nagasaka, Toshiaki Ohshima
    • Organizer
      The 1st International Symposium on Aquatic Product Processing
    • Place of Presentation
      IPB Convention Center, Bogor, Indonesia
    • Related Report
      2013 Research-status Report
  • [Presentation] ウシ血中の過酸化脂質およびエルゴチオネイン含量の関係2013

    • Author(s)
      孫 禎晧,長阪玲子,小山智之,大島敏明,松田秀雄,安藤貞
    • Organizer
      日本畜産学会第117回大会
    • Place of Presentation
      新潟大学五十嵐キャンパス
    • Related Report
      2013 Research-status Report
  • [Presentation] Anti- melanogenic effects of “enokitake” mushroom hydrophilic extract on B16 melanoma cells2013

    • Author(s)
      Yuki Ishikawa, Takumi Inada, Reiko Nagasaka, Tomoyuki Koyama, Toshiaki Ohshima
    • Organizer
      The 8th Asia Pacific Conference on Clinical Nutrition
    • Place of Presentation
      The Tokyo Bay Maihama Hotel Club
    • Related Report
      2013 Research-status Report
  • [Presentation] RBC Omega-3 Status of South Asian and Caucasian Canadians2013

    • Author(s)
      Nimal Ratnayake, Reiko Nagasaka, Claude Gagnon, Elenora Swist, Isabelle Rondeau, Patrick Laffey, Isabelle Massarelli, Winnie Cheung
    • Organizer
      104th AOCS annual meeting & Expo
    • Place of Presentation
      Palais des congres de Montreal
    • Related Report
      2013 Research-status Report
  • [Presentation] Effects of Maturity Stage and Post-harvest storage condition on the ergothineine and phenolic contents, and antioxidative properties of selected mushroom varieties2013

    • Author(s)
      The Han Nguyen, Reiko Nagasaka, Tomoyuki Koyama, Toshiaki Ohshima
    • Organizer
      104th AOCS annual meeting & Expo
    • Place of Presentation
      Palais des congres de Montreal
    • Related Report
      2013 Research-status Report
  • [Book] 日本食およびその素材の健康機能性開発2016

    • Author(s)
      長阪玲子他
    • Total Pages
      277
    • Publisher
      シーエムシー出版
    • Related Report
      2016 Research-status Report
  • [Book] Lipid Oxidation: Challenges in Food Systems2013

    • Author(s)
      The Han Nguyen, Reiko Nagasaka, Toshiaki Ohshima
    • Total Pages
      549
    • Publisher
      AOCS press
    • Related Report
      2013 Research-status Report
  • [Patent(Industrial Property Rights)] 水溶性切削液2015

    • Inventor(s)
      長阪 玲子,黒瀬 雅詞,岡安 武蔵, 奈良 力男,澤本 悟博
    • Industrial Property Rights Holder
      長阪 玲子,黒瀬 雅詞,岡安 武蔵, 奈良 力男,澤本 悟博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-12-25
    • Related Report
      2015 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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