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A system for identifying QTL candidate genes in livestock using published microarray data

Research Project

Project/Area Number 25850185
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Animal production science
Research InstitutionKyoto University

Principal Investigator

Matsuda Hirokazu  京都大学, (連合)農学研究科(研究院), 助教 (30597810)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
KeywordsQTL候補遺伝子 / 公共データベース / 網羅的遺伝子発現データ / RNA共発現情報 / SNP共関連情報 / 黒毛和種 / 飼料利用性 / 遺伝子ネットワーク / 発現QTL / アノテーション情報 / データマイニング
Outline of Final Research Achievements

In model organisms, high quality of gene annotation is available and it is possible to quickly identify candidate genes for the quantitative trait of interest. But its use is restricted in livestock due to poor annotation. Recently, microarray and next-generation sequencing technologies have generated high-throughput gene expression data that are collected in public database for multiple species. This study develops a system for identifying QTL candidate genes in livestock using published microarray data. Here, focusing on mouse and cattle, we investigated the usefulness of current system for predicting phenotypes and estimating a reliable gene network.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2016 2015 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (2 results)

  • [Journal Article] Predicting the Phenotypic Values of Physiological Traits Using SNP Genotype and Gene Expression Data in Mice2014

    • Author(s)
      Yu Takagi, Hirokazu Matsuda, Yukio Taniguchi, Hiroaki Iwaisaki
    • Journal Title

      PLOS ONE

      Volume: 9巻 Issue: 12 Pages: e115532-e115532

    • DOI

      10.1371/journal.pone.0115532

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] SNP共関連およびRNA共発現の情報を利用した遺伝子ネットワークの推定2016

    • Author(s)
      岡田大瑚、遠藤聡子、松田洋和、小川伸一郎、谷口幸雄、勝田智博、渡邊敏夫、杉本喜憲、祝前博明
    • Organizer
      日本畜産学会
    • Place of Presentation
      日本獣医生命科学大学キャンパス(東京都武蔵野市)
    • Year and Date
      2016-03-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] 黒毛和種直接検定牛を対象とした飼料利用性に関する遺伝子ネットワーク推定の試み2015

    • Author(s)
      遠藤聡子、松田洋和、谷口幸雄、勝田智博、渡邊敏夫、杉本喜憲、祝前博明
    • Organizer
      日本畜産学会
    • Place of Presentation
      宇都宮大学 峰キャンパス(栃木県宇都宮市)
    • Year and Date
      2015-03-28 – 2015-03-30
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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