| Project/Area Number |
25850196
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Veterinary medical science
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 原虫 / 細胞表面タンパク質 / 細胞接着 / 細胞表面蛋白質 / 質量分析 / 細胞表面分子 / 感染症 / ベクター / 宿主 |
|---|
| Outline of Final Research Achievements |
This study aimed at identification of cell adhesion molecules of Trypanosoma congolense epimastigotes and bloodstream forms, and isolation of candidate molecules with biochemical and molecular methods followed by its identification with mass spectrometry analyses were carried out. As the result of that, several surface proteins of unknown function and one unknown protein interacting with sialic acid were yielded as candidate proteins from epimastigotes and bloodstream forms, respectively.
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