Comprehensive analysis of oncogenic viruses in canine lymphoma

• Project/Area Number: 25850208
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Veterinary medical science
• Research Institution: Yamaguchi University
• Principal Investigator: Baba Kenji 山口大学, 共同獣医学部, 准教授 (90452367)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: リンパ腫 / イヌ / 腫瘍ウイルス / 腫瘍 / ウイルス / 犬

Outline of Final Research Achievements

In this study, viral involvement was investigated in canine lymphoma. No virus was found in the tumor cells from dogs with naturally occurring lymphoma by comprehensive analysis. The prevalence of Epstein-Barr virus (EBV) known as an oncogenic virus in some forms of human lymphoma was very low in canine lymphoma. In summary, viral involvement seemed to be less common in canine lymphoma.

Research Products

• [Journal Article] Oncolytic reovirus in canine mast cell tumor. (2013)
  • Author(s): Hwang CC, Umeki S, Kubo M, Hayashi T, Shimoda H, Mochizuki M, Maeda K, Baba K, Hiraoka H, Coffey M, Okuda M, Mizuno T
  • Journal Title: Plos One Volume: 8 Issue: 9 Pages: e73555-e73555
  • DOI: 10.1371/journal.pone.0073555
  • Peer Reviewed