| Project/Area Number |
25860032
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Physical pharmacy
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| Research Institution | Hyogo University of Health Sciences |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | カドミウムイオン / 蛍光プローブ / カドミウム / 有害重金属 |
|---|
| Outline of Final Research Achievements |
To develop a fluorescent probe for simple and sensitive detection of cadmium, recognized as a highly toxic heavy metal, we have constructed a basic structure of an irreversible fluorescent probe for cadmium ions. Moreover, we have developed a practical fluorescent probe for cadmium ions based on coordination chemistry, and demonstrated that it allows highly sensitive and selective detection of cadmium ions. It has also been shown that the probe is applicable to cadmium ion imaging in living cells.
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