Research Project
Grant-in-Aid for Young Scientists (B)
The aim is to identify the molecular mechanism which regulates intercellular crosstalk by SOCS box protein SSB.We identified SSB-binding proteins. Given that SSB is a ubiquitin ligase, we checked the stability of SSB-binding proteins and found that one of the candidate accumulated by knockdown of SSB. The candidate has been reported as a tumor suppressor gene and also as a oncogene. We are currently studying the physiological function of the candidate protein.
All 2014 2013
All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results)
J Biol Chem.
Volume: 289(30) Pages: 20970-20978