| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
In this research project, we have focused on the system that the specific glycoproteins carry the specific glycans such as LewisX and HNK-1 carbohydrates, and attempted to elucidate the molecular mechanism underlying the definite glycosylation in neural stem cells. Furthermore, we have identified the molecule interacted with a specific glycan-possessing protein. The fact raises the possibility that a specific combination of glycans and their carrier proteins involved in the signaling pathways for the maintenance and differentiation of neural stem cells.
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