Novel methods for the quality evaluation of Angelicae Radix aimed to expansion of Japanese production
| Project/Area Number |
25860077
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Natural medicines
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| Research Institution | Kanazawa University |
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Principal Investigator |
SASAKI Yohei 金沢大学, 薬学系, 准教授 (10366833)
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| Research Collaborator |
UENO Mutsumi 金沢大学, 大学院医薬保健学総合研究科
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 当帰 / 品質評価 / メタボローム解析 / トウキ / 品質評価法 / 国内生産 / 栽培研究 |
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| Outline of Final Research Achievements |
Angelicae Radix is produced via traditional processes like drying in outside and steeping in hot water after cultivation in some aria in Japan. As those processes are thought to be the cause of quality differences, it is necessary to establish the method to make an analysis the Angelicae Radix. Here, I divided Angelicae Radix into five parts; root head, insides of main root, outside of main root, lateral-root and terminal lateral-root. I analyzed the contents of ethanol-extracts, the contents of Ligustilide, and the constituents and contents of sugars; glucose, fructose, sucrose. Using the Angelicae Radix produced by three kinds of condition; no steeping in hot water, steeping in 45 and 70 degree.
As a result, ethanol extract contents are superior in main root to other pats and increasing by warming at 45 or 70 degree. Ligstilide contents were revealed to be rich in head part of main roots. In this study we newly established the technique to check a quality by the different process.
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Report
(3 results)
Research Products
(2 results)
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[Presentation] 当帰の品質評価に関する研究2014
Author(s)
上野睦美，三宅克典、佐々木陽平
Organizer
日本生薬学会第６１回年会
Place of Presentation
福岡大学薬学部、福岡市
Year and Date
2014-09-13 – 2014-09-14
Related Report
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