Investigation of the mechanism of alcohol withdrawal symptom with ethanol-injected mouse model
| Project/Area Number |
25860098
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Environmental and hygienic pharmacy
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| Research Institution | Josai International University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | アルコール依存症 / 離脱症状 / 不安症 / うつ病 / エピジェネティクス |
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| Outline of Final Research Achievements |
Alcoholism is the common disorder. Although the medical treatment of alcoholism is to stop drinking an alcohol beverage, alcohol withdrawal symptom disrupt it. The purpose of this research is investigation of the mechanism of alcohol withdrawal symptom. In order to construct an animal model in which the symptom of alcoholism is assessed, we injected ethanol solution into mice chronically and observed the alcohol withdrawal behavior. Alcohol withdrawal behavior such as anxiety and depression was observed with several behavior test.
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Report
(4 results)
Research Products
(1 results)
