Salivaly oxytocin concentration as a more simplified measurement method of endogenious oxytocin concentration than plasma
| Project/Area Number |
25860110
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical pharmacy
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | オキシトシン / 自閉スペクトラム症 / 自閉症スペクトラム障害 / 血液検体 / 唾液検体 |
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| Outline of Final Research Achievements |
Recent reserches have reported that secretion of oxytocin in autism spectrum disorder (ASD) was disrupted and oxytocin has the potential for therapeutic medication of ASD. Uintil now, plasma oxytocin measurement has been used for measuring peripheral oxytocin concentration. However, because it needs blood withdrawal, more simplified and low-invasive methods are expected. Wherein, The purpose of this study was to reveal the correlation between salivary and plasma oxytocin for establishing salivary oxytocin measurement as a low-invasive method for measuring peripheral oxytocin.
We collected samples from 73 typically developing adults and finished the analysis 21 of them. It was found that significant correlation between plasma and salivaly oxytocin. So we propose that we can use saliva in low-invasive peripheral oxytocin measurment instead of plasma. We presented this at an academic meeting. Then we are still continuing the rest of analysis even now.
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Report
(3 results)
Research Products
(4 results)
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[Presentation] 青年期ASD者における視線計測と血漿オキシトシン濃度の関連2014
Author(s)
升谷 泰裕, 岡本 悠子, 藤澤 隆史, 田仲志保, 新井 清義, 浅野 みずき, 丁 ミンヨン, 石川 俊介, 藤岡徹, 石飛 信, 松村 由紀子, 友田明美, 小坂 浩隆, 石飛信
Organizer
第55回日本児童青年精神医学会
Place of Presentation
浜松市アクトシティ浜松
Year and Date
2014-10-12
Related Report
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[Presentation] Relationship between gaze fixations and oxytocin levels in adults with autism spectrum disorders: an eye-tracking study.2014
Author(s)
Inohara K, Fujisawa TX, Masuya Y, Asano M, Ishitobi M, Saito DN, Jung M, Arai S, Matsumura Y, Tomoda A, Wada Y, Kosaka H.
Organizer
International Workshop on Molecular Functional Imaging for Brain and Gynecologic Oncology
Place of Presentation
福井県、ユアーズホテルフクイ
Related Report
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