Morphological analysis of circuitry of cholinergic C-terminal inputs to oro-facial motor neurons
Project/Area Number |
25860152
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
General anatomy (including histology/embryology)
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Research Institution | National Defense Medical College |
Principal Investigator |
MATSUI Toshiyasu 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 助教 (90531343)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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Keywords | 運動ニューロン / 脳幹網様体 / コリン作動性ニューロン / 脳神経運動核 / 神経トレーサー / 介在ニューロン / ウイルスベクター / partition細胞 |
Outline of Final Research Achievements |
Large cholinergic synaptic boutons, named C-terminals, contact motor neurons innervating oro-facial muscles and regulate their excitability. In the present study, we first determined the distribution of cholinergic interneurons that gave rise to C-terminals in oro-facial motor nuclei, using neuronal tracing techniques. Next, we produced viral vectors for the tracer to visualize cholinergic neurons in a single-cell level, and examined morphological characteristics of cholinergic interneurons that are origins of C-terminals in the spinal cord.
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Report
(4 results)
Research Products
(10 results)
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[Presentation] レーザー誘起衝撃波を利用した難聴耳鳴モデル2015
Author(s)
Katsuki Niwa, Kunio Mizutari, Toshiyasu Matsui, Takaomi Kurioka, Takeshi Matsunobu, Atsushi Tamura, Satoko Kawauchi, Yasushi Sato, Shunichi Sato, Akihiro Shiotani, Yasushi Kobayashi
Organizer
第38回日本神経科学大会
Place of Presentation
神戸
Year and Date
2015-07-28
Related Report
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