| Project/Area Number |
25860387
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical sociology
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
NAWATA Masao 産業医科大学, 医学部, 非常勤医師 (20389430)
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| Co-Investigator(Renkei-kenkyūsha) |
SAITO Kazuyoshi 産業医科大学, 医学部, 准教授 (30279327)
TANAKA Yoshiya 産業医科大学, 医学部, 教授 (30248562)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 関節リウマチ / メソトレキサート / 寛解 / 臨床的寛解 / 機能的寛解 / 職業的寛解 / TNF阻害薬 / 休薬 / 構造的寛解 / メトトレキサート |
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| Outline of Final Research Achievements |
I accumulate continuously a case to correspond to the standard that I showed for a study plan and the method. I analyzed the case using the TNF inhibitor at the same time. At first I performed a stratified analysis for the period of time of the impact between the 10-year use results period, and I analyzed patient backgrounds at the time of the TNF inhibitor baseline. In addition, I analyzed it about MTX of the TNF inhibitor combination and examined the most suitable usage of MTX. Furthermore, I paid my attention about bio-free remission of the TNF inhibitor and analyzed it about a factor (patient backgrounds, blood test levels, disease activity, Amount of change of joint preserving effects (Yearly progression) ) at baseline, discontinuation, and after discontinuation.
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