| Project/Area Number |
25860434
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Hokkaido University |
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Principal Investigator |
ITO Sachiko 北海道大学, 環境健康科学研究教育センター, 特任助教 (90580936)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 環境疫学 / 予防医学 / 社会医学 / 疫学・予防医学 |
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| Outline of Final Research Achievements |
In a prospective birth cohort study, there was no statistical difference between any of the SNPs related to metabolic pathway and OH-PCB concentrations in maternal blood during pregnancy. We conducted multiple linear regression models to estimate the effects of maternal exposure to OH-PCBs on thyroid hormone statuses (TSH, FT4) of mother and infant. Statistical significant associations were found between maternal 4-OH-CB187 concentrations and maternal FT4, and maternalΣOH-PCB, 4-OH-CB187 and infant FT4 among only males. We measured the concentration of adiponectin and leptin in cord blood samples.
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