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The confounding effect of cryptic relatedness in epidemiology.

Research Project

Project/Area Number 25860436
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Epidemiology and preventive medicine
Research InstitutionKanazawa University (2016)
Tohoku University (2013-2015)

Principal Investigator

Shibata Kyoko  金沢大学, 附属病院, 特任准教授 (90535600)

Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords血縁構造 / 血縁構造化 / 交絡因子
Outline of Final Research Achievements

We investigated the confounding effect of unadjusted cryptic relatedness among a rural cohort in the relationship between environmental risk factors and quantitative traits interms of sample size, the prevalence, the helitability of liability, the effect size of environmental risk factores. We found a confounding effect of cryptic relatedness in the relationship between quantitative trait and environmnetal risk factors was not negligible.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (1 results)

All 2014

All Presentation (1 results)

  • [Presentation] The simulation of the confounding effect on cryptic relatedness for environmental risks in cohort studies.2014

    • Author(s)
      Kyoko Shibata, Akimichi Tatsukawa, Soichi Ogishima, Kazuro Shimokawa, Satoshi Nagaie, Naoki Nakamura, Jun Nakaya
    • Organizer
      米国人類遺伝学会
    • Place of Presentation
      米国サンディエゴ
    • Year and Date
      2014-10-18 – 2014-10-22
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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