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Exposure to tobacco smoke during childhood in relation to obesity and oxidative stress.

Research Project

Project/Area Number 25860461
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Hygiene and public health
Research InstitutionGifu University

Principal Investigator

WADA Keiko  岐阜大学, 医学(系)研究科(研究院), 准教授 (00532673)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords受動喫煙 / 肥満 / 酸化ストレス / 内因性ホルモン / 小児 / 疫学
Outline of Final Research Achievements

We purposed to investigate the associations of exposures to tobacco smoke during childhood with child’s health status and the development of chronic diseases later in life.
About 600 preschool children and 2400 elementary students participated in the study. Their parents reported their smoking status in detail in the questionnaire, and children provided first-void morning urine. Whether other family members smoked at home were also inquired. Exposure to tobacco smoke during pregnancy of the index child was evaluated. Some students underwent medical health check-up including blood drawing. Height, weight, blood pressure, fasting glucose, triglyceride, and cholesterol were examined.
The associations between passive smoking assessed by the questionnaire and urinary cotinine levels were assessed. Whether exposure to smoke assessed by these two methods was associated with oxdative stress markers, body mass, blood pressure, sex hormone levels were investigated.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (8 results)

All 2015 2014 2013

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Acknowledgement Compliant: 2 results,  Open Access: 1 results) Presentation (4 results)

  • [Journal Article] Soy isoflavone intake and stomach cancer risk in Japan: From the Takayama study.2015

    • Author(s)
      Wada K, Tsuji M, Tamura T, Konishi K, Kawachi T, Hori A, Tanabashi S, Matsushita S, Tokimitsu N,Nagata C.
    • Journal Title

      Int J Cancer.

      Volume: 印刷中 Issue: 4 Pages: 885-892

    • DOI

      10.1002/ijc.29437

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Husband's smoking status and breast cancer risk in Japan: From the Takayama study.2015

    • Author(s)
      Wada K, Kawachi T, Hori A, Takeyama N, Tanabashi S, Matsushita S, Tokimitsu N,Nagata C.
    • Journal Title

      Cancer Sci.

      Volume: 106(4) Issue: 4 Pages: 455-60

    • DOI

      10.1111/cas.12619

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Body mass index and breast cancer risk in Japan: a pooled analysis of eight population-based cohort studies.2014

    • Author(s)
      Wada K, Nagata C, Tamakoshi A, Matsuo K, Oze I, Wakai K, Tsuji I, Sugawara Y, Mizoue T, Tanaka K, Iwasaki M, Inoue M, Tsugane S, Sasazuki S; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.
    • Journal Title

      Ann Oncol.

      Volume: 25(2) Issue: 2 Pages: 519-24

    • DOI

      10.1093/annonc/mdt542

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Associations of endogenous melatonin and sleep-related factors with behavioral problems in preschool Japanese children.2013

    • Author(s)
      Wada K, Nakamura K, Tamai Y, Tsuji M, Watanabe K, Ando K, Nagata C.
    • Journal Title

      Ann Epidemiol.

      Volume: 23 Issue: 8 Pages: 469-474

    • DOI

      10.1016/j.annepidem.2013.05.013

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Alcohol intake during pregnancy and offspring’s atopic eczema2015

    • Author(s)
      和田恵子、中村こず枝、田村高志、小西希恵、白木誠、岩砂眞一、永田知里
    • Organizer
      日本疫学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-01-21 – 2015-01-23
    • Related Report
      2014 Annual Research Report
  • [Presentation] イソフラボン摂取と胃がんリスク:高山スタディ2014

    • Author(s)
      和田恵子、辻美智子、小西希恵、田村高志、永田知里
    • Organizer
      がん予防学術大会 2014
    • Place of Presentation
      東京
    • Year and Date
      2014-06-13 – 2014-06-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] 出生時要因、乳児期の栄養法が幼児期の行動に及ぼす影響について2014

    • Author(s)
      和田恵子、辻美智子、中村こず枝、渡辺香織、大土早紀子、山本景子、安藤京子、永田知里
    • Organizer
      日本疫学会学術総会
    • Place of Presentation
      仙台
    • Related Report
      2013 Research-status Report
  • [Presentation] 海苔摂取が幼児期の性ホルモン値に及ぼす影響について2013

    • Author(s)
      和田恵子、玉井裕也、出原啓一、辻美智子、中村こず枝、大土早紀子、山本景子、渡辺香織、安藤京子、永田知里
    • Organizer
      日本がん疫学・分子疫学研究会総会
    • Place of Presentation
      岐阜
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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