Development of the simultaneous analysis system of compounds contained in herbal blend products and these metabolites or decompositions
| Project/Area Number |
25860475
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Hygiene and public health
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| Research Institution | Osaka Prefectural Institute of Public Health |
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Principal Investigator |
Asada Akiko 大阪府立公衆衛生研究所, 衛生化学部, 研究員 (80622753)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 違法ドラッグ / 危険ドラッグ |
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| Outline of Final Research Achievements |
Designer drug is a serious social problem in recent years. This study aimed to develop the system for analysis of chemical compounds contained in herbal blend products and to identify the metabolites or decompositions arising from these compounds. As a result, we analyzed more than 350 of drug components by GC-MS, LC-PDA, and LC-QTOF/MS. In addition, we clarified the structures of decomposition or by-product in herbal blend products by instrumental analysis and proposed the mechanism of their production.
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Report
(4 results)
Research Products
(10 results)
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[Journal Article] Identification and characterization of α-PVT, α-PBT, and their bromothienyl analogs found in illicit drug products2016
Author(s)
Takahiro Doi, Akiko Asada, Akihiro Takeda, Takaomi Tagami, Munehiro Katagi,Shuntaro Matsuta, Hiroe Kamata, Masami Kawaguchi,Yuka Satsuki, Yoshiyuki Sawabe,Hirotaka Obana
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Journal Title
Forensic Toxicol
Volume: 34
Issue: 1
Pages: 76-93
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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