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Establishment of measures to prevent hospital infections due to spore-forming bacteria

Research Project

Project/Area Number 25860482
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical and hospital managemen
Research InstitutionJichi Medical University

Principal Investigator

Sasahara Teppei  自治医科大学, 医学部, 講師 (30448849)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords感染対策 / 芽胞産生菌 / 病院環境 / 院内感染 / 手指衛生 / 院内感染制御 / 病院環境汚染 / 感染制御
Outline of Final Research Achievements

Hospital environments were evaluated for bacterial spore contamination, and risk factors for the contamination was analyzed. The environments around 35% of the patients who had Clostridium difficile infections (CDI) were contaminated with CD spores. The spores were detected from the high-frequency contact objects, and not from the environments around non-CDI patients. The stool culture positive for CD was suspected as a risk factor for the contamination. PFGE analysis suggested that specific strain of CD had spread among the ward for the long term. Bacillus subtilis and B. cereus were widely detected from the environments around 86% of the all subjects. Medical staff were also evaluated for the contamination. Spores were detected on the hands of 76.1% of them. There was a significant negative correlation between the contamination level and the frequency of handwashing. Our results suggest that medical staff should wash their hands more than twice/hour to prevent spore contamination.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (4 results)

All 2016 2015 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (3 results)

  • [Journal Article] Contamination of healthcare workers’ hands with bacterial spores2016

    • Author(s)
      Teppei Sasaharaa, Ryusuke Ae, Michiyo Watanabe, Yumiko Kimura, Chikara Yonekawa, Shunji Hayashi, Yuji Morisawa
    • Journal Title

      Journal of infection and chemotherapy

      Volume: 印刷中 Issue: 8 Pages: 521-525

    • DOI

      10.1016/j.jiac.2016.04.007

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Clostridium difficile感染患者周囲環境の芽胞汚染2016

    • Author(s)
      笹原鉄平、渡辺美智代、山越裕美、林俊治、森澤雄司
    • Organizer
      第31回日本環境感染学会総会学術集会
    • Place of Presentation
      国立京都国際会館・グランドプリンスホテル京都(京都)
    • Year and Date
      2016-02-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] Investigation and control measures of Bacillus cereus outbreak due to contaminated hospital linens2015

    • Author(s)
      Teppei Sasahara, Shunji Hayashi, Yuji Morisawa, Yoshikazu Hirai
    • Organizer
      第88回日本細菌学会総会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Research-status Report
  • [Presentation] 医療スタッフにおける手指衛生と手指芽胞汚染の関係2014

    • Author(s)
      笹原鉄平,菅原香織,渡辺美智代,稲川秀樹,林俊治,森澤雄司,平井義一
    • Organizer
      第29回日本環境感染学会総会学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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