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A study of inhibitory effect of alcohol on the return of spontaneous circulation using a rat model of cardiopulmonary arrest

Research Project

Project/Area Number 25860489
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Legal medicine
Research InstitutionKochi University

Principal Investigator

FURUMIYA Junichi  高知大学, 教育研究部医療学系, 准教授 (60363280)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords心肺蘇生法 / 飲酒者 / 心拍再開 / 救急医学 / 法医学
Outline of Final Research Achievements

We investigated whether drinking alcohol has adverse effects on the ability to return of spontaneous circulation (ROSC) by cardiopulmonary resuscitation (CPR) after cardiac arrest. We used a rat model of cardiopulmonary arrest. Three minutes after cessation of natural breathing by hypoxic exposure, CPR with chest compression and oxygen administration were performed to the model rats. There were no significant difference of the rate of ROSC between a group of ethanol administration and a group of saline administration. However, the time between start of hypoxic exposure and cessation of natural breathing in a group of ethanol administration was significantly shorter than that in a group of saline administration. This phenomenon may affect that the rate of ROSC in ethanol groups and a control group are similar.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (2 results)

All 2014 2013

All Presentation (2 results) (of which Invited: 1 results)

  • [Presentation] 法医実務からみた飲酒心停止傷病者2014

    • Author(s)
      古宮淳一
    • Organizer
      第49回日本アルコール・薬物医学会 シンポジウム
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2014-10-03
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 低酸素曝露心停止ラットの心肺蘇生における病態解析2013

    • Author(s)
      古宮淳一、西村拡起、中西祥徳、橋本良明
    • Organizer
      第97次日本法医学会学術全国集会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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