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Molecular biological approach to thymic stromal cell in involuted thymus

Research Project

Project/Area Number 25860495
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Legal medicine
Research InstitutionOsaka Medical College

Principal Investigator

Shuntaro Abe  大阪医科大学, 医学部, 助教 (80335116)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords胸腺 / ストレス / 児童虐待 / ストローマ細胞 / 胸腺ストローマ細胞 / インターロイキン
Outline of Final Research Achievements

Immunostaining for leptin receptor and interleukin-7 receptor were performed in involuted thymus obtained from forensic autopsy. However, differences in cause of stress between involuted and control thymus were not detected. However, result of this research may be useful for elucidation of Hassall's corpuscle function and cause of fibril formation at stress induced involuted thymus.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (2 results)

All 2016 2015

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results) Presentation (1 results)

  • [Journal Article] Evaluation of thymic volume by postmortem computed tomography.2015

    • Author(s)
      Abe S, Hasegawa I, Vogel H, Heinemann A, Suzuki K, Pschel K.
    • Journal Title

      Leg Med (Tokyo)

      Volume: 17 Issue: 4 Pages: 251-4

    • DOI

      10.1016/j.legalmed.2015.02.006

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] 法医剖検例における心臓血中レプチン濃度の検討2016

    • Author(s)
      阿部俊太郎,佐藤貴子,齊藤高志,野村和克,坪井健人,北川美佐,鈴木廣一
    • Organizer
      日本法医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2016-06-16
    • Related Report
      2015 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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