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Development of computer-aided diagnostic system by using endocytoscopy

Research Project

Project/Area Number 25860564
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Gastroenterology
Research InstitutionShowa University

Principal Investigator

MORI Yuichi  昭和大学, 医学部, 助教 (20459209)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsコンピュータ診断支援 / 自動診断 / 大腸癌 / 大腸ポリープ / 大腸内視鏡 / endocytoscopy / 顕微内視鏡 / コンピュータ補助診断 / 多変量解析 / 内視鏡 / 超拡大内視鏡
Outline of Final Research Achievements

"Objective endoscopic diagnosis" not only leads to improvement of medical quality,but also contributes to suppression of medical costs by decreasing pathological examination, thus its realization is desired. We developed computer-aided diagnostic system by using ultra-magnifying endoscopy in order to realize objective diagnosis. Our research lead the following results;1. Based on in vivo analysis of nuclei, we succeeded in automatic diagnosis of colon polyps. 2. We realized real-time pathological prediction. 3. Differentiation of neoplastic change was achieved with an accuracy of 89% (Mori Y, Kudo S, et al.Gastrointest Endosc 2015).
Further research are needed for practical use of this system.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (22 results)

All 2015 2014 2013 Other

All Journal Article (9 results) (of which Peer Reviewed: 6 results,  Open Access: 5 results,  Acknowledgement Compliant: 1 results) Presentation (12 results) (of which Invited: 3 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Novel computer-aided diagnostic system for colorectal lesions using endocytoscopy (with videos)2015

    • Author(s)
      Mori Y, Kudo SE, Wakamura K, Misawa M, Ogawa Y, Kutsukawa M, Kudo T, Hayashi T, Miyachi H, Ishida F, Inoue H.
    • Journal Title

      Gastrointest Endosc

      Volume: 81 Issue: 3 Pages: 621-9

    • DOI

      10.1016/j.gie.2014.09.008

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Diagnostic performance of endocytoscopy for evaluating the invasion depth of different morphological types of colorectal tumors.2015

    • Author(s)
      Kudo T, Kudo SE, Wakamura K, Mori Y, Misawa M, Hayashi T, Kutsukawa M, Ichimasa K, Miyachi H, Ishida F, Inoue H.
    • Journal Title

      Dig Endosc

      Volume: in press Issue: 7 Pages: 755-762

    • DOI

      10.1111/den.12469

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Endocytoscopic narrow-band imaging efficiency for inflammatory activity evaluation in ulcerative colitis: A pilot study.2014

    • Author(s)
      Maeda Y, Ohtsuka K, Kudo SE, Wakamura K, Mori Y, Ogata N, Wada Y, Misawa M, Yamauchi A, Hayashi S, Kudo T, Hayashi T, Miyachi H, Yamamura F, Ishida F, Inoue H, Hamatani S.
    • Journal Title

      World J Gastroenterol

      Volume: 21 Issue: 7 Pages: 2108-15

    • DOI

      10.3748/wjg.v21.i7.2108

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Efficiency of endocytoscopy in differentiating among types of serrated polyps2014

    • Author(s)
      Kutsukawa M, Kudo S, Ikehara N, Mori Y, et al.
    • Journal Title

      Gastrointest Endosc

      Volume: 79 Issue: 4 Pages: 648-656

    • DOI

      10.1016/j.gie.2013.08.029

    • Related Report
      2014 Annual Research Report 2013 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Endocytoscopy can provide additional diagnostic ability to magnifying chromoendoscopy for colorectal neoplasms.2014

    • Author(s)
      Kudo S, Mori Y, Wakamura K, et al.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 29 Issue: 1 Pages: 83-90

    • DOI

      10.1111/jgh.12374

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Double staining with crystal violet and methylene blue is appropriate for colonic endocytoscopy: an in vivo prospective pilot study.2014

    • Author(s)
      Ichimasa K, Kudo SE, Mori Y, Wakamura K, Ikehara N, Kutsukawa M, Takeda K, Misawa M, Kudo T, Miyachi H, Yamamura F, Ohkoshi S, Hamatani S, Inoue H
    • Journal Title

      Dig Endosc

      Volume: 14 Issue: 3 Pages: 403-8

    • DOI

      10.1111/den.12164

    • Related Report
      2013 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 大腸におけるEndocytoscopy2014

    • Author(s)
      工藤進英, 森 悠一, 若村邦彦.
    • Journal Title

      日本臨床

      Volume: 72 Pages: 565-572

    • Related Report
      2013 Research-status Report
  • [Journal Article] 次世代内視鏡への展望: Endocytoscopyによる大腸腫瘍・大腸癌の診断-.2013

    • Author(s)
      森 悠一, 工藤進英, 若村邦彦.
    • Journal Title

      癌の臨床

      Volume: 59 Pages: 395-403

    • Related Report
      2013 Research-status Report
  • [Journal Article] 超拡大内視鏡(Endocytoscopy)による大腸腫瘍の診断法2013

    • Author(s)
      工藤進英, 若村邦彦, 森 悠一
    • Journal Title

      Gastroenterological Endoscopy

      Volume: 55 Pages: 1510-1517

    • NAID

      10031169199

    • Related Report
      2013 Research-status Report
  • [Presentation] 大腸Endocytoscopyによるコンピュータ自動診断システムの新規開発2014

    • Author(s)
      森 悠一, et al.
    • Organizer
      JDDW2014
    • Place of Presentation
      神戸
    • Year and Date
      2014-10-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] Novel computer-aided diagnosis system for colorectal lesions using endocytoscopy.2014

    • Author(s)
      Mori Y et al.
    • Organizer
      UEGW2014
    • Place of Presentation
      Vienna
    • Year and Date
      2014-10-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] 大腸Endocytoscopyによるコンピュータ自動診断システム2014

    • Author(s)
      森 悠一, et al
    • Organizer
      JAMIT2014
    • Place of Presentation
      東京
    • Year and Date
      2014-07-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 大腸Endocytoscopyによるコンピュータ自動診断システム2014

    • Author(s)
      森 悠一, et al
    • Organizer
      第87回日本内視鏡学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-17
    • Related Report
      2014 Annual Research Report
  • [Presentation] Novel computer-aided diagnosis system for colorectal lesions using endocytoscopy.2014

    • Author(s)
      Mori Y et al.
    • Organizer
      6th Magnifying Endoscopy Conference
    • Place of Presentation
      Chicago
    • Year and Date
      2014-05-06
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Novel computer-aided diagnosis system for colorectal lesions using endocytoscopy.2014

    • Author(s)
      Mori Y et al.
    • Organizer
      DDW2014
    • Place of Presentation
      Chicago
    • Year and Date
      2014-05-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 大腸におけるEndocytoscopy

    • Author(s)
      森 悠一
    • Organizer
      第13回 colon imaging academy
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Endocytoscopyによる、in vivoでの核のサイズ計測による組織類推

    • Author(s)
      森 悠一
    • Organizer
      JDDW2013
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] Novel computer-aided diagnosis system for colorectal lesions using endocytoscopy

    • Author(s)
      Mori Y
    • Organizer
      6th Magnifying Endoscopy Conference
    • Place of Presentation
      Chicago
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Novel computer-aided diagnosis system for colorectal lesions using endocytoscopy

    • Author(s)
      Mori Y
    • Organizer
      DDW2014
    • Place of Presentation
      Chicago
    • Related Report
      2013 Research-status Report
  • [Presentation] 大腸Endocytoscopyによるコンピュータ自動診断システム

    • Author(s)
      森 悠一
    • Organizer
      JAMIT2014
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] 大腸Endocytoscopyによるコンピュータ自動診断システム

    • Author(s)
      森 悠一
    • Organizer
      第87回日本内視鏡学会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Patent(Industrial Property Rights)] 画像処理装置及び画像処理方法2015

    • Inventor(s)
      森 悠一、三澤将史、工藤進英、脇坂隆史
    • Industrial Property Rights Holder
      森 悠一、三澤将史、工藤進英、脇坂隆史
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-036771
    • Filing Date
      2015-02-26
    • Related Report
      2014 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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