| Project/Area Number |
25860630
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|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Cardiovascular medicine
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|---|
| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
NAGAI Toshiyuki 独立行政法人国立循環器病研究センター, 病院, 医師 (00528218)
|
|---|
| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 心臓サルコイドーシス / 早期診断 / 多面的アプローチ |
|---|
| Outline of Final Research Achievements |
Approximately 13% of extracardiac sarcoidosis patients without cardiac manifestation had myocardial damage defined by late gadollinuum enhancement cardiac magnetic resonance imaging (LGE-CMR), however, this small myocardial damage might not be associated with worse clinical outcomes (Chest 2014; 146: 1064). Futhermore, in additional retrospective analyses, the long-term effect of corticosteroid therapy (Circ J 2015, in press) and the prognostic significance of basal interventricular thinning (Circ J 2015, in press) have also been clarified. These findings will provide the key data for establishment of diagnostic and treatment guidelines in patients with sarcoidosis.
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