| Project/Area Number |
25860664
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
KIDO Takashi 産業医科大学, 医学部, 講師 (30389465)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 電子顕微鏡 / 石綿 / 粉塵 / 肺線維症 / びまん性肺疾患 / 成分解析 / 光学顕微鏡 / 気管支肺胞洗浄液 / びまん性肺疾患患者 / 間質性肺炎 / 職業性呼吸器疾患 / 職業性肺疾患 / 粉じん |
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| Outline of Final Research Achievements |
We have evaluated the utility of electron microscopy in the analysis of asbesots, fibers and particles in bronchoalveolar lavage fluid (BALF) of 107 patients with diffuse lung diseases incluiding pulmonary fibrosis. In the detection of asbestos, electron microscopy using BALF seemed to be superior to light microscopy using BALF and displayed a similar sensitivity to light microscopy using surgically-obtained lung tissue samples. Our results also suggest that detection of elements in particles is useful for evaluating occupational exposure.
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