Assessment of energy expenditure in pediatric cases treated with hypothermia

Research Project

Project/Area Number	25860875
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Pediatrics
Research Institution	Yokohama City University
Principal Investigator	Watanabe Yoshihiro 横浜市立大学, 大学病院, 助教 (30621544)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000) Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000) Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords	脳低温療法 / 栄養 / 間接熱量測定 / 小児脳低温療法
Outline of Final Research Achievements	Hypothermia therapy has been thought to be effective for various cerebral injuries in children. Much of the nutritional management under hypothermia therapy is based on empirical rules. It is needed that the method of objective evaluation establishes. In three cases which treated by hypothermia therapy, we measured the prescription necessary energy amount using an indirect calorimeter. The volume of oxygen consumption and carbon dioxide production were measured by each tenses (cooling period, during rewarming period, and after rewarming). We calculated resting energy expenditure (REE) using method of Weir. As a result, REE in cooling period was decreased 46.1-82.2% than that in after rewarming.