Identification of the most vulnerable cell type in fetal brain, and development of a new treatment for fetal brain injury with growth factors
Project/Area Number |
25860906
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Embryonic/Neonatal medicine
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Research Institution | Nagoya University |
Principal Investigator |
Ito Miharu 名古屋大学, 医学(系)研究科(研究院), 特任助教 (60570083)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Keywords | 胎児発育不全 / 胎児発育遅延 / 子宮内胎児発育遅延 / 子宮内発育遅延(FGR) / 虚血感受性細胞種 / 増殖・栄養因子 |
Outline of Final Research Achievements |
Recently, it was shown that fetal growth restriction (FGR) is high risk for learning and/or behavioral problems, such as impaired motor coordination, learning disability, depression, and/or attention-deficit hyperactivity disorder. Impaired vascular perfusion in fetal period, which is one of the etiology of FGR, can cause to white matter injury. In this project, we developed two FGR models with impaired vascular perfusion in fetal period, and evaluated them histologically and behaviorally.
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Report
(4 results)
Research Products
(10 results)
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[Journal Article] Surgical approaches for neonatal congenital diaphragmatic hernia: a systematic review and meta-analysis.2015
Author(s)
Terui K, Nagata K, Ito M, Yamoto M, Shiraishi M, Taguchi T, Hayakawa M, Okuyama H, Yoshida H, Masumoto K, Kanamori Y, Goishi K, Urushihara N, Kawataki M, Inamura N, Kimura O, Okazaki T, Toyoshima K, Usui N.
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Journal Title
Pediatr Surg Int
Volume: 31(10)
Issue: 10
Pages: 891-7
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Presentation] Holoprosencephalyの新生児期脳波とaEEG2014
Author(s)
伊藤 美春, 杉山 裕一朗, 鈴木 俊彦, 孫田 みゆき, 近藤 大貴, 齊藤 明子, 中村 祐子, 藤巻 英彦, 佐藤 義朗, 早川 昌弘, 小川 千香子, 山本 啓之, 城所 博之, 夏目 淳
Organizer
第44回胎児新生児神経研究会
Place of Presentation
順天堂大学(東京都文京区)
Related Report
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[Presentation] 先天性横隔膜ヘルニアにおける生後早期の胸部レントゲン所見と予後との関連2013
Author(s)
伊藤 美春, 杉山 裕一朗, 鈴木 俊彦, 近藤 大貴, 齊藤 明子, 服部 哲夫, 中村 祐子, 藤巻 英彦, 佐藤 義朗, 早川 昌弘, 津田 弘之
Organizer
第58回未熟児新生児学会・学術集会
Place of Presentation
石川県立音楽堂, ANAクラウンプラザホテル金沢, ホテル金沢(金沢市)
Related Report
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