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A Study on appropriate nutritional management for the IUGR new born and risk of metabolic syndrome

Research Project

Project/Area Number 25860916
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Embryonic/Neonatal medicine
Research InstitutionOsaka Prefecture University

Principal Investigator

Kondo Tomohiro  大阪府立大学, 生命環境科学研究科(系), 助教 (40585238)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords子宮内胎児発育遅延 / 栄養管理 / 高血圧 / 腎臓 / 未熟児医学 / 糸球体硬化 / メタボリックシンドローム
Outline of Final Research Achievements

The effective nutritional management to low birth weight infants by intrauterine growth restriction (IUGR) does not become clear yet. In this study, new nutritional management methods to introduce the protein intake restriction after the catch-up growth was examined what kind of influence on the mainly hypertension among the metabolic syndrome. The nutritional management to IUGR model mice was found to reduce hypertension risk without affecting growth. Also, the nutritional management has been suggested that exert a positive influence on obesity and hyperlipidemia.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (6 results)

All 2016 2015 2014 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (5 results)

  • [Journal Article] Maternal protein restriction that does not have an influence on the birthweight of the offspring induces morphological changes in kidneys reminiscent of phenotypes exhibited by intrauterine growth retardation rats.2016

    • Author(s)
      Yuasa K, Kondo T, Nagai H, Mino M, Takeshita A, Okada T.
    • Journal Title

      Congenit Anom

      Volume: 56 Issue: 2 Pages: 79-85

    • DOI

      10.1111/cga.12143

    • NAID

      130008079216

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 子宮内胎児発育遅延(IUGR)マウス新生子の腎臓および血圧に対する生後蛋白質摂取制限の影響2016

    • Author(s)
      岡田 利也、繁村 綾佑、長井 寛明、武下 愛、三野 将城、日下部 健、近藤 友宏
    • Organizer
      第56回日本先天異常学会学術集会
    • Place of Presentation
      姫路商工会議所(兵庫県姫路市)
    • Year and Date
      2016-07-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] 子宮内胎児発育遅延(IUGR)マウス新生子への栄養管理が成熟後の腎臓に及ぼす影響2015

    • Author(s)
      吉留翔哉、長井寛明、武下愛、日下部健、岡田利也、近藤友宏
    • Organizer
      第158回日本獣医学会学術集会
    • Place of Presentation
      北里大学獣医学部(青森県十和田市)
    • Year and Date
      2015-09-07
    • Related Report
      2015 Annual Research Report
  • [Presentation] 子宮内胎児発育遅延(IUGR)マウス新生子の腎臓の発達:蛋白摂取制限による影響2014

    • Author(s)
      近藤友宏、繁村綾佑、長井寛明、武下愛、三野将城、日下部健、岡田利也
    • Organizer
      第157回日本獣医学会学術集会
    • Place of Presentation
      北海道大学 札幌
    • Year and Date
      2014-09-09 – 2014-09-12
    • Related Report
      2014 Research-status Report
  • [Presentation] 子宮内胎児発育遅延(IUGR)マウス新生子の腎臓に関する形態学的観察2014

    • Author(s)
      岡田利也、繁村綾佑、長井寛明、武下愛、三野将城、日下部健、近藤友宏
    • Organizer
      第119回日本解剖学会総会・全国学術集会
    • Place of Presentation
      自治医科大学 下野市
    • Related Report
      2013 Research-status Report
  • [Presentation] 子宮内胎児発育遅延(IUGR)モデルマウス新生子の腎臓に関する形態学的観察2013

    • Author(s)
      繁村綾佑、岡田利也、武下愛、三野将城、日下部健、近藤友宏
    • Organizer
      第156回日本獣医学会学術集会
    • Place of Presentation
      岐阜大学 岐阜市
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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