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Seroprevalence of Human Herpesvirus 8 in Miyako Islands; the endemic area of Kaposi's sarcoma

Research Project

Project/Area Number 25860961
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Dermatology
Research InstitutionUniversity of the Ryukyus

Principal Investigator

HAYASHI Kentaro  琉球大学, 医学部附属病院, 助教 (50631991)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordsカポジ肉腫 / HHV8 / ヒトヘルペスウイルス8型 / 沖縄 / 宮古 / ウイルス発癌 / 宮古島 / カポシ肉腫 / ヒトヘルペス8型ウイルス / 血管肉腫
Outline of Final Research Achievements

We found the high seropositivity of human herpesvirus 8 (HHV8) in the population of Miyako Islands, where people have a greater chance of developing non-AIDS associated Kaposi’s sarcoma. The seroprevalence of HHV8 was 15.37% in Miyako Island,that is approximately 11 times higher than those of Okinawa Islands and Japan. The prevalence rate increased with age, and there was little difference between men and women (16.55% and 14.10%).
Meanwhile, estimated incidence of non-AIDS associated Kaposi’s sarcoma was about 35 times higher in Miyako Islands than that in Okinawa Islands. These date support the hypothesis that the additional factors, such as the variants of HHV8 virus or the presence of host genetic factors, other than HHV8 infection rate, may be involved in Kaposi’s sarcoma development.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (10 results)

All 2014 2013 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Open Access: 5 results) Presentation (5 results)

  • [Journal Article] A Case of a Pilomatricoma Associated with Myotonic Dystrophy Being Suspected for Squamous Cell Carcinoma2014

    • Author(s)
      大久保 優子, 内海 大介, 苅谷 嘉之, 林 健太郎, 粟沢 剛, 眞鳥 繁隆, 高橋 健造, 上里 博
    • Journal Title

      Nishi Nihon Hifuka

      Volume: 76 Issue: 4 Pages: 353-356

    • DOI

      10.2336/nishinihonhifu.76.353

    • NAID

      130004695271

    • ISSN
      0386-9784, 1880-4047
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 仙骨部の褥瘡,褥瘡瘢痕に生じた有棘細胞癌の3例2014

    • Author(s)
      眞鳥 繁隆, 粟澤 遼子, 林 健太郎, 粟澤 剛, 平良 清人, 高橋 健造, 上里 博
    • Journal Title

      臨床皮膚科

      Volume: 68 Pages: 815-819

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Blastic Plasmacytoid Dendritic Cell Neoplasm 芽球性形質細胞様樹状細胞腫瘍の2例2014

    • Author(s)
      白瀬 春奈, 山口 さやか, 平良 清人, 林 健太郎, 苅谷 嘉之, 山本 雄一, 高橋 健造, 上里 博
    • Journal Title

      臨床皮膚科

      Volume: 76 Pages: 577-582

    • NAID

      130005065017

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 【隆起する皮膚疾患】 <臨床例>隆起性皮膚線維肉腫2014

    • Author(s)
      林 健太郎, 仲村 郁心, 眞鳥 繁隆, 高橋 健造, 上里 博
    • Journal Title

      皮膚病診療

      Volume: 36 Pages: 547-550

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Early Onset of Acute Compartment Syndrome Diagnosed by a Simple Needle Manometer Technique2013

    • Author(s)
      眞鳥 繁隆, 宮城 拓也, 花城 ふく子, 園崎 哲, 林 健太郎, 粟澤 剛, 苅谷 嘉之, 高橋 健造, 上里 博
    • Journal Title

      Nishi Nihon Hifuka

      Volume: 76 Issue: 5 Pages: 454-458

    • DOI

      10.2336/nishinihonhifu.76.454

    • NAID

      130004831890

    • ISSN
      0386-9784, 1880-4047
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 先天性異所爪の1例2013

    • Author(s)
      﨑枝薫、粟澤剛、林健太郎、苅谷嘉之 他
    • Organizer
      日本皮膚科学会第67回沖縄地方会
    • Place of Presentation
      沖縄県那覇市
    • Related Report
      2013 Research-status Report
  • [Presentation] カルバマゼピンによる薬剤性過敏症症候群が疑われた1例

    • Author(s)
      玉城祐一郎、宮城拓也、粟澤剛、川畑有香、林健太郎 他
    • Organizer
      日本皮膚科学会第66回沖縄地方会
    • Place of Presentation
      沖縄県中頭郡西原町
    • Related Report
      2013 Research-status Report
  • [Presentation] 当科における新型V.A.C治療システムの使用経験

    • Author(s)
      川畑有香、粟澤剛、眞鳥繁隆、林健太郎 他
    • Organizer
      日本皮膚科学会第66回沖縄地方会
    • Place of Presentation
      沖縄県中頭郡西原町
    • Related Report
      2013 Research-status Report
  • [Presentation] 当院での悪性黒色のセンチネルリンパ節生検について

    • Author(s)
      眞鳥繁隆、山城充士、川畑有香、林健太郎 他
    • Organizer
      日本皮膚科学会第68回沖縄地方会
    • Place of Presentation
      沖縄県那覇市
    • Related Report
      2013 Research-status Report
  • [Presentation] 隆起性皮膚線維肉腫の1例

    • Author(s)
      大平葵、仲村郁心、川畑有香、林健太郎 他
    • Organizer
      日本皮膚科学会第69回沖縄地方会
    • Place of Presentation
      沖縄県那覇市
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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