| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
|---|
| Outline of Final Research Achievements |
Sensory gating is one of the brain information processing systems and regulates enormous sensory input to the brain. P50 inhibition is assessed by recording P50, which is a positive wave peaking between 40 and 75 ms following auditory stimulus presentation, in response to two paired auditory stimuli, and is assumed to reflect sensory gating.
The aim of the present study was to examine the association between dysfunction of sensory gating and the pathophysiology of psychiatric disorders such as panic disorder. The main result was that anxiety-related core symptoms, anxiety, fear and tension of the subcategories of the Hamilton Anxiety Rating Scale (HAM-A) were not significant but showed a trend of positive correlation with P50 test/condition ratio in patients with panic disorder (Pearson's r = 0.340, p = 0.083). This finding implicated that dysfunction of sensory gating might contribute to the pathophysiology of anxiety.
|
