The role of cytokines in the pathophysiology of autism and depression
Project/Area Number |
25860997
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Psychiatric science
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Research Institution | Shinshu University |
Principal Investigator |
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Project Period (FY) |
2013-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Keywords | 自閉症スペクトラム / サイトカイン / 認知機能 / うつ病 / autism spectrum disorder / cytokine / depression |
Outline of Final Research Achievements |
Evidence indicates that immune system and nervous system reciprocally regulate each other through cytokines. Previous reports have shown that some cytokines are increased in patients with autism spectrum disorder (ASD). In the present study, we showed that children with ASD who had higher blood levels of interleukin-6 (IL-6) had lower verbal comprehension scores. This finding suggests the possibility that IL-6 may play a role in the impairment of cognitive development in those with ASD.
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Report
(3 results)
Research Products
(1 results)