• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

development of new treatment for depression using neurofeedback by NIRS

Research Project

Project/Area Number 25861011
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Psychiatric science
Research InstitutionYamaguchi University

Principal Investigator

MATSUBARA Toshio  山口大学, 大学教育機構, 准教授 (60526896)

Research Collaborator MATSUO Koji  山口大学, 大学院医学系研究科, 准教授 (00292912)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywordsニューロフィードバック / 前頭葉 / 血流変化 / 光トポグラフィー / うつ病 / neurofeedback / 光トポグラフィ- / mindfulness / NIRS / depression / emotion
Outline of Final Research Achievements

Neurofeedback is an approach that uses neuroimaging techniques to acquire real-time measures of brain activity and learn self-regulation of brain function. Patients with major depressive disorder show dysfunction of frontal lobe to emotional stimuli. Hence, it could be a new treatment technique to improve the dysfunction by NF in patients with depression. We used near-infrared spectroscopy to evaluate brain function and perform neurofeedback. First, we demonstrated brain dysfunction to emotional stimuli in the patients with depression. Second, we showed that healthy participants demonstrated elevated frontal brain activation by neurofeedback.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (8 results)

All 2016 2015 2014 2013

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (7 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Prefrontal activation in response to emotional words in patients with bipolar disorder and major depressive disorder2014

    • Author(s)
      Matsubara T, Matsuo K, Nakashima M, Nakano M, Harada K, Watanuki T, Egashira K, Watanabe Y.
    • Journal Title

      Neuroimage

      Volume: 15 Pages: 489-497

    • DOI

      10.1016/j.neuroimage.2013.04.098

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 健常人における情動文課題中の近赤外線スペクトロスコピィを用いたニューロフィードバック2016

    • Author(s)
      松原敏郎,松尾幸治,平田圭子,原田健一郎 ,綿貫俊夫 ,渡邉義文
    • Organizer
      第38回日本生物学的精神医学会
    • Place of Presentation
      福岡市,福岡国際会議場
    • Year and Date
      2016-09-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] Different fronto-temporal activation during emotional and cognitive tasks in patients with unipolar and bipolar depression: A functional near-infrared spectroscopy study2016

    • Author(s)
      T Matsubara, K Matsuo, K Harada, M Nakashima, M Nakano, M Hirotsu, K Hirata, N Higuchi, T Watanuki, F Higuchi, H Yamagata, Y Watanabe
    • Organizer
      18th ISBD and 8th ISAD
    • Place of Presentation
      Amsterdam, The Netherlands
    • Year and Date
      2016-07-13
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Different fronto-temporal activation during an emotional words task in patients with unipolar and bipolar depression:A functional near-infrared spectroscopy study2015

    • Author(s)
      Toshio Matsubara
    • Organizer
      Society of Biological Psychiatry
    • Place of Presentation
      toronto, Canada
    • Year and Date
      2015-05-14
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 寛解状態の気分障害患者における情動顔刺激に対する脳血流動態変化の検討2014

    • Author(s)
      松原敏郎,松尾幸治,原田健一郎,中島麻美,中野雅之,綿貫俊夫,渡邉義文
    • Organizer
      第36回日本生物学的精神神経医学会
    • Place of Presentation
      奈良文化会館(奈良県奈良市)
    • Year and Date
      2014-09-29 – 2014-10-01
    • Related Report
      2014 Research-status Report
  • [Presentation] 近赤外線スペクトロスコピィ検査(NIRS)を用いた高齢者うつ病における脳機能の検討2014

    • Author(s)
      松原敏郎、松尾幸治、原田健一郎、中島麻美、綿貫俊夫、渡邉義文
    • Organizer
      第11回日本うつ病学会
    • Place of Presentation
      広島国際会議場(広島県広島市)
    • Year and Date
      2014-07-18 – 2014-07-19
    • Related Report
      2014 Research-status Report
  • [Presentation] Morphometric Abnormalities in Unaffected First-degree Relatives of Mood Disorders.2014

    • Author(s)
      T Matsubara, K Matsuo, M Nakashima, K Harada, M Nakano, K Egashira, T Watanuki, Y Watanabe
    • Organizer
      69th Society of Biological Psychiatry
    • Place of Presentation
      N.Y.(USA)
    • Year and Date
      2014-05-08 – 2014-05-10
    • Related Report
      2014 Research-status Report
  • [Presentation] Differential patterns of abnormal brain activation to emotional words in individuals with bipolar disorder and major depressive disorder in remission.2013

    • Author(s)
      Matsubara T
    • Organizer
      10th World Congress of Biological Psychiatry
    • Place of Presentation
      京都(国立京都国際会館)
    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi