Effects of cognitive rehabilitation using original computer software in schizophrenia: a randomized controlled trial

Research Project

Project/Area Number	25861024
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Psychiatric science
Research Institution	Nara Medical University
Principal Investigator	MATSUDA Yasuhiro 奈良県立医科大学, 医学部, 助教 (70445063)
Research Collaborator	MORIMOTO Tsubasa 奈良県立医科大学, 医員 (90613795)
Project Period (FY)	2013-04-01 – 2015-03-31
Project Status	Completed (Fiscal Year 2014)
Budget Amount *help	¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2014: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000) Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords	統合失調症 / 認知機能 / 認知機能リハビリテーション / コンピュータソフト / JCORES / 心理社会的治療
Outline of Final Research Achievements	We have developed the original computer software which provided practice across a broad range of cognitive functioning, including psychomotor speed, attention, memory, executive functions, and fluency. This study examined whether cognitive rehabilitation using original computer software is more effective than the standard treatment in both cognitive and social functioning. Subjects were engaged in 2 sessions of the cognitive training per week for 12 weeks and took part in 1 session of bridging group per week for 12 weeks. Thirty-nine outpatients with schizophrenia were randomized to either a cognitive rehabilitation group (CRG, n=22) or treatment as usual group (TAU, n=17). Negative symptom, general psychopathology, verbal memory, executive functions and BACS composite score show significantly higher in CRG than in TAU. However the improvement of cognitive function doesn’t reach the improvement of social functions.