| Project/Area Number |
25861032
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Nihon University |
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Principal Investigator |
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| Research Collaborator |
UCHIYAMA Makoto
KONNO Michiko
YAMADA Koju
KAKEKO Yoshiyuki
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| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | うつ病 / 覚醒療法 / 光療法 / 時間生物学 / 高照度光療法 / 断眠療法 |
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| Outline of Final Research Achievements |
Several methods for heightening and sustaining the antidepressant effect of wake therapy (sleep deprivation) have recently been reported. In this study, we investigated the effect of repeated sleep deprivation combined with bright light therapy on drug-resistant depression. Our treatment protocol resulted in a sustained antidepressant effect on drug-resistant depression. No special equipment is needed for wake therapy; therefore, it could be a new treatment option for drug-resistant depression in both psychiatric hospitals and clinics.
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